ea0015p288 | Reproduction | SFEBES2008
Barber Thomas
, Bennett Amanda
, Groves Christopher
, Sovio Ulla
, Ruokonen Aimo
, Martikainen Hannu
, Pouta Anneli
, Hartikainen Anna-Liisa
, Elliott Paul
, Lindgren Cecilia
, Freathy Rachel
, Koch Kirsten
, Ouwehand Willem
, Karpe Fredrik
, Conway Gerard
, Wass John
, Jarvelin Marjo-Riitta
, Franks Stephen
, McCarthy Mark
Background: Obesity plays an important role in the aetiology of polycystic ovary syndrome (PCOS). Variants in the fat-mass and obesity-associated (FTO) gene have recently been shown to influence adiposity and predispose to common obesity (Frayling et al., Science 2007 316 889894).Aim: Our aim was to establish whether FTO variants are also implicated in PCOS-susceptibility.Methods: A genetic ...